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| # | Club | Pld | W | D | L | GF | GA | GD | Pts | Form |
|---|---|---|---|---|---|---|---|---|---|---|
| 1 |  Vancouver Whitecaps | 14 | 10 | 2 | 2 | 34 | 12 | +22 | 32 | WLWDD |
| 2 |  San Jose Earthquakes | 15 | 10 | 2 | 3 | 34 | 15 | +19 | 32 | WLLDD |
| 3 |  Real Salt Lake | 14 | 8 | 2 | 4 | 26 | 19 | +7 | 26 | DWWLW |
| 4 |  FC Dallas | 15 | 7 | 4 | 4 | 30 | 22 | +8 | 25 | WWLWW |
| 5 |  Los Angeles FC | 15 | 7 | 3 | 5 | 24 | 17 | +7 | 24 | WLLLD |
| 6 |  Seattle Sounders | 13 | 7 | 3 | 3 | 17 | 11 | +6 | 24 | LLWDD |
| 7 |  Houston Dynamo | 14 | 7 | 1 | 6 | 19 | 23 | -4 | 22 | DWLWW |
| 8 |  Minnesota United FC | 15 | 6 | 4 | 5 | 18 | 22 | -4 | 22 | DLLDW |
| 9 |  Los Angeles Galaxy | 15 | 5 | 5 | 5 | 22 | 22 | 0 | 20 | DWLWD |
| 10 |  San Diego | 15 | 4 | 5 | 6 | 30 | 27 | +3 | 17 | LDWDD |
| 11 |  Colorado Rapids | 15 | 5 | 1 | 9 | 25 | 24 | +1 | 16 | LLWLL |
| 12 |  St. Louis City | 14 | 4 | 4 | 6 | 16 | 20 | -4 | 16 | WDWWL |
| 13 |  Portland Timbers | 14 | 4 | 2 | 8 | 22 | 28 | -6 | 14 | LLDWL |
| 14 |  Austin | 15 | 3 | 5 | 7 | 19 | 31 | -12 | 14 | LLLDW |
| 15 |  Sporting Kansas City | 14 | 3 | 2 | 9 | 14 | 36 | -22 | 11 | LWWLD |
| # | Club | Pld | W | D | L | GF | GA | GD | Pts | Form |
|---|---|---|---|---|---|---|---|---|---|---|
| 1 |  Nashville SC | 14 | 10 | 3 | 1 | 31 | 11 | +20 | 33 | WWWDD |
| 2 |  Inter Miami | 15 | 9 | 4 | 2 | 39 | 28 | +11 | 31 | WWWWL |
| 3 |  Chicago Fire | 14 | 8 | 2 | 4 | 27 | 16 | +11 | 26 | WWWLL |
| 4 |  New England Revolution | 14 | 8 | 1 | 5 | 22 | 18 | +4 | 25 | LWLWW |
| 5 |  New York Red Bulls | 15 | 6 | 4 | 5 | 25 | 32 | -7 | 22 | WDWWL |
| 6 |  Charlotte | 15 | 6 | 3 | 6 | 24 | 23 | +1 | 21 | WWLDL |
| 7 |  FC Cincinnati | 15 | 5 | 5 | 5 | 36 | 37 | -1 | 20 | WDLDW |
| 8 |  New York City FC | 15 | 5 | 4 | 6 | 25 | 21 | +4 | 19 | LDWWL |
| 9 |  DC United | 15 | 4 | 6 | 5 | 21 | 25 | -4 | 18 | DDLDW |
| 10 |  Columbus Crew | 15 | 4 | 4 | 7 | 21 | 23 | -2 | 16 | WDLLL |
| 11 |  CF Montreal | 14 | 4 | 2 | 8 | 22 | 31 | -9 | 14 | DLDWL |
| 12 |  Orlando City SC | 15 | 4 | 2 | 9 | 23 | 44 | -21 | 14 | LDWLW |
| 13 |  Toronto FC | 14 | 3 | 5 | 6 | 22 | 29 | -7 | 14 | LLLDL |
| 14 |  Atlanta United FC | 14 | 3 | 2 | 9 | 14 | 23 | -9 | 11 | LDLWW |
| 15 |  Philadelphia Union | 15 | 1 | 4 | 10 | 18 | 30 | -12 | 7 | LDLLD |
| # | Team | Group | Pld | GD | Pts |
|---|---|---|---|---|---|
| 1 | Chicago Fire | Eastern Conference | 14 | +11 | 26 |
| 2 | Real Salt Lake | Western Conference | 14 | +7 | 26 |